Bisquick Impossible Pizza Pie

Featured in: Satisfying Hearty Mains

Ground beef and onions browned with Italian seasonings, combined with pepperoni and marinara, layered with cheese in a pie pan, topped with Bisquick batter and more pepperoni, baked until golden.

Tags: #beef #cheese

Clare Greco
Updated on Tue, 08 Sep 2026 16:00:37 GMT
Bisquick Impossible Pizza Pie
Bisquick Impossible Pizza Pie | recipesbyclare.com
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Bisquick impossible pizza pie layers seasoned beef, pepperoni, marinara, and mozzarella beneath a simple baking-mix batter. As the pie bakes, the liquid mixture settles through the filling and forms a tender supporting crust, giving familiar pizza flavors the structure of an easy casserole.

The recipe serves six and takes about 35 minutes. Draining the beef and pepperoni well prevents an oily pie, while even layering and a short rest produce cleaner wedges. It is designed for a 9-inch pie pan and a 400°F oven, making it a practical weeknight dinner when a rolled crust is not on the schedule.

Ingredients for Impossible Pizza Pie

Ingredients for impossible pizza pie with beef, onion, pepperoni, marinara, mozzarella, baking mix, eggs, milk, seasonings, garlic, and cooking oil
Ingredients for impossible pizza pie with beef, onion, pepperoni, marinara, mozzarella, baking mix, eggs, milk, seasonings, garlic, and cooking oil | Recipes by Clare
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The meat filling uses 1 pound ground beef, one diced onion, 1/2 teaspoon each salt and black pepper, 1 teaspoon each paprika, Italian seasoning, and onion powder, 1/4 teaspoon crushed red pepper, 1 tablespoon minced garlic, 1 cup marinara, and 1/4 cup chopped pepperoni plus extra slices for the top.

Whisk 1/2 cup Bisquick-style baking mix with 2 eggs and 3/4 cup milk. Assembly needs 2 cups shredded mozzarella and cooking spray. Because pepperoni, marinara, cheese, and baking mix contain salt, taste the cooked filling before adding more.

How to Make Bisquick Impossible Pizza Pie

Four stages showing beef onion and pepperoni cooked, baking mix batter whisked, meat and mozzarella layered in a pie dish, and batter poured over before baking
Four stages showing beef onion and pepperoni cooked, baking mix batter whisked, meat and mozzarella layered in a pie dish, and batter poured over before baking | Recipes by Clare
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  1. Heat the oven. Set it to 400°F and spray a 9-inch pie pan.
  2. Brown the beef. Cook beef and onion with salt, pepper, paprika, Italian seasoning, onion powder, and red pepper.
  3. Add pepperoni. Stir in chopped pieces for several minutes, then drain grease.
  4. Finish the filling. Add marinara and garlic, stir, and remove from heat.
  5. Whisk the batter. Combine baking mix, eggs, and milk until smooth.
  6. Layer. Add half the beef to the pan, then 1 cup mozzarella; repeat.
  7. Pour and top. Distribute batter over the layers and arrange extra pepperoni slices.
  8. Bake. Cook 25 minutes until golden, set in the center, and 160°F.
  9. Rest. Wait 10 minutes before slicing.

Brown the Beef Thoroughly

Use a broad skillet over medium-high heat and break the ground beef into small crumbles. Add onion and dry seasonings while the meat cooks so the spices bloom in the rendered fat.

Cook until no pink remains and the beef reaches 160°F. Small crumbles distribute more evenly through the pie and make wedges easier to cut.

Cook Chopped Pepperoni Briefly

Add the chopped pepperoni after the beef browns and cook for a few minutes. This renders excess fat and deepens the cured-meat flavor throughout the filling.

Drain safely, then stir in marinara and minced garlic. Removing the skillet from heat keeps the mixture from reducing too far while the batter is prepared.

Whisk a Smooth Batter

Whisk baking mix, eggs, and milk until no large dry pockets remain. Scrape the bottom of the bowl, where dry mix often hides, but do not beat longer than necessary.

A smooth, pourable batter settles around the layers and forms the characteristic base. Let it stand only briefly; prolonged resting can thicken it before pouring.

Prepare the Pie Pan Well

Coat the bottom and sides of a 9-inch pie pan with cooking spray. Pay attention to the rim where melted cheese can stick.

Use the specified pan size so the center and edges finish together. A deeper or smaller dish changes the batter depth and may require more time.

Layer for Even Wedges

Spread half the beef mixture across the prepared pan, add one cup mozzarella, then repeat with the remaining beef and cheese. Reach the edges rather than building a mound in the middle.

Even layers allow the batter to move through the filling and help each wedge contain similar amounts of meat and cheese.

Pour Batter Slowly

Pour the baking-mix batter in a slow circle over the entire surface. It may not look like a conventional crust before baking; that is expected.

Add the extra pepperoni slices without pressing them below the batter. Give the pan one gentle tap to release large air pockets, but do not stir the layers.

Golden impossible pizza pie with seasoned beef, pepperoni, marinara, and melted mozzarella
Golden impossible pizza pie with seasoned beef, pepperoni, marinara, and melted mozzarella | recipesbyclare.com
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Check the Center at 25 Minutes

The pie is done when the top is golden, the center does not ripple like liquid, and a thermometer reaches 160°F. Insert it away from the pan bottom for an accurate reading.

If the surface colors early, cover loosely with foil and continue until set. Ovens vary, so use visual and temperature checks rather than color alone.

Rest for Clean Slices

Allow about 10 minutes before cutting. The batter and cheese continue to set during this rest, giving the soft pie enough structure to hold a wedge.

Run a thin knife around the edge, cut through the pepperoni with a sharp blade, and lift portions with a pie server.

Serving and Variations

Serve with a crisp green salad, roasted vegetables, or extra warm marinara. A small amount of fresh basil or parsley adds color without making the pie heavier or masking its familiar pizza flavor.

Mushrooms or bell pepper may be sautéed with the onion, but carefully cook away their moisture completely before layering. Avoid piling raw watery vegetables into the pan.

Storage and Reheating

Refrigerate cooled wedges within two hours and use within three days. Reheat in a 325°F oven until steaming and 165°F in the center; cover loosely to prevent overbrowning.

A microwave is faster but softens the crust. Freeze well-wrapped individual wedges for up to two months and thaw overnight before reheating.

Troubleshooting

  • Pie is greasy: Drain beef and pepperoni thoroughly.
  • Center stays wet: Use a 9-inch pan and bake until 160°F.
  • Batter has lumps: Whisk and scrape the bowl before pouring.
  • Wedges collapse: Rest for 10 minutes before cutting.
  • Vegetables release water: Sauté them first and cool before layering.

Conclusion

Brown seasoned beef and onion, cook chopped pepperoni briefly, drain, and add marinara and garlic. Layer the filling with mozzarella in a sprayed pie pan, pour over a smooth baking-mix batter, top with pepperoni, and bake at 400°F until set.

Frequently Asked Questions

→ Why is it called impossible pizza pie?

The pourable baking-mix batter settles through the filling and forms its own supporting crust as it bakes.

→ How do I keep pizza pie from becoming greasy?

Cook the pepperoni briefly and drain the meat mixture thoroughly before adding marinara.

→ Can I add vegetables?

Yes. Sauté mushrooms or peppers first and remove excess moisture before layering.

→ How do I know the pie is done?

The center should be set, the top golden, and the internal temperature 160°F.

4.50 from 67 votes

Bisquick Impossible Pizza Pie

Preparation Time:
10 Minutes
Cook Time:
25 Minutes
Total Cooking Time:
35 Minutes
Number of Servings:
6
Bisquick Impossible Pizza Pie
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Ground beef, pepperoni, and mozzarella layered in a pie pan with Bisquick batter that forms a crust as it bakes.

Ingredients You'll Need

  • For the Meat Filling

  • For the Bisquick Mixture

  • For Assembly

How to Make It

1.

1. Cook the Beef: Brown the ground beef with the diced onion in a skillet over medium-high heat. Add all the seasonings - salt, pepper, paprika, Italian seasoning, onion powder, and crushed red pepper flakes.

2.

2. Add Pepperoni and Sauce: Once the beef is browned, add the chopped pepperoni and let it cook for a few minutes. Drain off any excess grease from the pan. Add the marinara sauce and minced garlic, stir well, then take the skillet off the heat.

3.

3. Make the Bisquick Mixture: In a bowl, whisk together the Bisquick, milk, and eggs until smooth.

4.

4. Layer in the Pie Pan: Spray a pie pan with cooking spray. Layer half of the ground beef mixture in the bottom, then top with 1 cup of the shredded mozzarella. Add the rest of the ground beef on top, then the remaining 1 cup of cheese.

5.

5. Add Bisquick and Toppings: Pour the Bisquick mixture evenly over the top of the ground beef and cheese layers. Top with additional pepperoni slices.

6.

6. Bake: Bake at 400 degrees for 25 minutes until the top is golden brown and set.

7.

7. Serve: Let it cool for a few minutes before slicing. Enjoy this fun twist on pizza!

Extra Information

  1. This is called an 'impossible pie' because the Bisquick mixture magically forms a crust as it bakes!
  2. Make sure to drain the grease well so the pie isn't too oily.
  3. You can customize the toppings - add mushrooms, bell peppers, or any pizza toppings you like.
  4. Leftovers keep in the fridge for up to 3 days and reheat well.

Essential Tools

  • Large skillet
  • 9-inch pie pan
  • Mixing bowl
  • Whisk

Allergy Warnings

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Contains dairy (milk, mozzarella cheese)
  • Contains eggs
  • Contains gluten (Bisquick)
  • Contains pork (pepperoni)

Nutrition Details (Per Portion)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 445
  • Total Fat: 28 g
  • Total Carbohydrate: 18 g
  • Protein: 30 g