Pepperoni Pizza Grilled Cheese

Featured in Irresistible Tasty Bites.

Quick 15-minute sandwich combining pizza toppings with grilled cheese. Buttery toasted bread filled with pepperoni, mozzarella, and marinara sauce.
Clare Greco
Updated on Tue, 04 Feb 2025 15:57:42 GMT
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Transform your kitchen into a pizzeria with this ingenious mashup of two comfort food favorites. This grilled cheese channels all the flavors of a pepperoni pizza, wrapped in toasty, buttery bread that'll have you reaching for seconds.

My kids went crazy the first time I made this. Now it's our Friday night tradition when we want pizza but don't want to wait for delivery.

Simple Ingredients Matter

  • Mozzarella cheese: Fresh is best for that perfect pizza stretch
  • Quality pizza sauce: The backbone of authentic pizza flavor
  • Pepperoni: Thin-sliced creates better texture
  • Good bread: Italian or sourdough makes all the difference
  • Real butter: Creates that perfect golden crust
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Detailed Instructions

Prep Work
Butter your bread generously
Have all ingredients ready
Get your pan nice and warm
Layer Building
Start with melty cheese base
Add your sauce carefully
Arrange pepperoni perfectly
Final Assembly
Top with remaining cheese
Press gently together
Keep heat medium-low
The Golden Finish
Watch for perfect browning
Listen for the sizzle
Feel for melted cheese

Last week my daughter had friends over, and these disappeared faster than actual pizza would have!

Complete The Meal

Serve with a caesar salad for the full pizzeria experience. A bowl of marinara sauce for dipping takes it over the top. For movie nights, I pair it with garlic knots and Italian sodas.

Make It Your Own

Add Italian herbs for extra flavor. Try different pizza toppings like mushrooms or bell peppers. Use provolone cheese for a sharper taste. Sometimes I add a sprinkle of red pepper flakes for heat.

Fresh From The Pan

These are best enjoyed immediately while the cheese is hot and stretchy. If you must save it for later, reheat in a pan to maintain the crispy exterior.

Ever since creating this recipe, it's become our go-to solution for pizza cravings. There's something magical about hearing that first crunch, then getting the perfect cheese pull. Even my Italian grandmother gave it her seal of approval!

The Perfect Meal

For a complete pizza experience, I serve these with a quick cucumber and tomato salad dressed in Italian vinaigrette. On game days, we make a batch alongside some garlic parmesan wings. Sometimes I'll throw together a simple antipasto platter with olives and marinated artichokes.

Creative Recipe Twists

Turn it into breakfast by adding a fried egg on top. Swap pepperoni for Italian sausage and add sautéed peppers. Make it vegetarian with spinach, mushrooms, and olives. My husband loves his with jalapeños and extra cheese for a spicy kick.

Leftover Love

While best fresh off the griddle, you can save it for later. Wrap in foil and reheat in a low oven to keep the bread crispy. The microwave works in a pinch but sacrifices the crunchy exterior. Pro tip: make extra and pack in lunch boxes - they're surprisingly good at room temperature.

Beyond The Basic

Try using garlic butter instead of plain butter on the bread. Add a layer of fresh basil leaves after cooking. Experiment with different cheese combinations - smoked mozzarella adds amazing depth. Some days I'll brush the outside with mayo instead of butter for extra crispiness.

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More Kitchen Magic

Transform it into sliders using dinner rolls. Create a breakfast version with scrambled eggs inside. Make it supreme style with all your favorite pizza toppings. During summer, add fresh tomatoes and basil for a margherita spin.

The beauty of this sandwich lies in its simplicity and familiarity. It brings together everything we love about pizza and grilled cheese into one perfect handful. Whether it's a quick lunch or late-night craving, this recipe never disappoints. It's become such a staple in our house that we keep pepperoni on hand just for these sandwiches!

Frequently Asked Questions

→ Can I add other pizza toppings?
Yes! Try adding cooked mushrooms, onions, or bell peppers. Just avoid wet ingredients that could make the bread soggy.
→ What's the best bread to use?
Any sturdy bread works well - Italian bread, sourdough, or white bread are all great choices that can hold the fillings.
→ Can I use different cheese?
While mozzarella gives the most pizza-like taste, you can mix in provolone or parmesan for extra flavor.
→ How do I prevent the sauce from making the bread soggy?
Use a moderate amount of sauce and place it between layers of cheese, which helps prevent the bread from getting soggy.
→ Can I make this ahead of time?
This sandwich is best served fresh and hot off the griddle when the cheese is melty and the bread is crispy.

Quick Pizza Grilled Cheese

Classic pizza flavors in a crispy grilled cheese sandwich, loaded with pepperoni, melted mozzarella, and marinara sauce.

Prep Time
5 Minutes
Cook Time
10 Minutes
Total Time
15 Minutes

Category: Tasty Bites

Difficulty: Easy

Cuisine: American

Yield: 1 Servings (1 sandwich)

Dietary: ~

Ingredients

→ Sandwich Ingredients

01 1 tablespoon butter
02 2 slices bread
03 2 slices mozzarella (or 1/2 cup shredded)
04 2 tablespoons pizza sauce or marinara sauce
05 1/2 ounce pepperoni

Instructions

Step 01

Heat a pan over medium heat.

Step 02

Butter one side of each bread slice. Place one slice buttered-side down in pan. Layer with half the cheese, half the sauce, all pepperoni, remaining sauce, and remaining cheese. Top with second bread slice, buttered-side up.

Step 03

Cook until golden brown and cheese melts, about 2-4 minutes per side.

Notes

  1. Layer cheese next to bread to prevent sogginess
  2. Best served immediately while hot and melty

Tools You'll Need

  • Skillet or griddle
  • Spatula

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Contains dairy (butter, cheese)
  • Contains gluten (bread)

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 513
  • Total Fat: 32 g
  • Total Carbohydrate: 32 g
  • Protein: 22 g