
This Southern baked macaroni and cheese completely changed my understanding of what mac and cheese could be. We're talking about a creamy, extra-saucy base loaded with five different cheeses, topped with a crispy, golden layer that's basically cheese heaven. After years of making regular stovetop mac and cheese, I tried this recipe for a family reunion and watched grown adults literally fight over the last scoop. Now it's become my signature dish that people specifically request whenever there's a potluck or special occasion.
My husband's grandmother, who's been making mac and cheese for seventy years, took one bite of this and declared it better than hers. Coming from a woman who's never admitted anyone else's cooking was superior, that was basically a miracle. Now she asks me to bring this to every family dinner instead of making her own.
What Makes It Special
- Medium cheddar: Provides that classic mac and cheese flavor everyone expects
- Colby Jack and mozzarella: Add creaminess and that perfect stretchy texture
- Sharp and white cheddar: Bring complexity and depth to the cheese blend
- Cream cheese: Makes everything incredibly smooth and rich
- Heavy cream and half-and-half: Create that luxurious, restaurant-quality sauce
- Secret seasonings: Mustard powder, paprika, and onion powder elevate the whole thing

Making It Happen
- Getting your setup ready
- Before you start anything else, shred all your cheeses and set aside 1 cup each of medium cheddar, Colby Jack, and mozzarella for the top layer. Preheat your oven to 425°F and get a 9x13 casserole dish ready. Cook your pasta just slightly less than al dente, it'll finish cooking in the oven, so you don't want it mushy.
- Creating the sauce base
- In a large skillet, melt 5 tablespoons of butter over medium-high heat and sauté the minced garlic for about a minute until it smells amazing. Whisk in the flour and keep stirring until it turns golden, this creates the roux that'll thicken your sauce. Slowly add the reserved pasta water, heavy cream, and half-and-half while whisking constantly to prevent lumps.
- The cheese magic
- Turn the heat down to low and start adding your cheeses one handful at a time, whisking constantly until each addition is completely melted before adding more. This takes patience, but it's what creates that incredibly smooth sauce. Finish by whisking in the cream cheese and all your seasonings until everything's perfectly combined.
- Assembly and baking
- Toss your cooked pasta with 2 tablespoons of butter in your casserole dish, then pour that incredible cheese sauce over everything and mix well. Top with your reserved cheeses and bake for 10 minutes. Switch to broil for the last 5 minutes to get that perfect crispy, golden top layer.
I learned the hard way that using pre-shredded cheese just doesn't work for this recipe. My first attempt resulted in a grainy, weird texture that was nothing like the smooth, creamy sauce this recipe is supposed to create. Now I always shred fresh cheese and get perfect results every time.
Perfect Serving Ideas
This mac and cheese is rich enough to be a main dish, but it's incredible alongside barbecue, fried chicken, or any Southern-style meal. A simple green salad or some steamed vegetables help balance out all that richness. For beverages, sweet tea is traditional, but honestly, cold beer or even wine works great too.
Making It Different
You can customize this by adding cooked bacon, ham, or lobster to make it even more special. Sometimes I throw in some jalapeños for heat, or use different cheese combinations based on what I have available. The base recipe is so good that almost any addition works well.
Make-Ahead Tips
This is perfect for entertaining because you can assemble everything up to the point of baking and refrigerate overnight. Just add an extra 10-15 minutes to the baking time if you're starting from cold. The flavors actually get better after sitting, so it's ideal for meal planning.

This Southern baked macaroni and cheese has become more than just a recipe in our house - it's become a tradition. Every time I make it, I'm reminded why some dishes become legendary in families. The combination of multiple cheeses, that perfect creamy-to-crispy ratio, and those special seasonings creates something that's way more than the sum of its parts. It's the kind of comfort food that makes people feel loved and taken care of, which is really what good cooking is all about.
Frequently Asked Questions
- → Why do you use five different types of cheese?
- Each cheese brings something unique - sharp cheddar for tang, mozzarella for stretch, Colby Jack for creaminess. The blend creates incredible depth of flavor.
- → Can I make this ahead of time?
- You can assemble it and refrigerate for up to 24 hours before baking. Add 10-15 extra minutes to the baking time if starting from cold.
- → What if I don't have all five types of cheese?
- You can substitute with similar cheeses, but try to use at least 3-4 different types for the best flavor complexity. Avoid pre-shredded if possible.
- → How do I prevent the cheese sauce from breaking?
- Keep heat low when adding cheese, add it gradually one handful at a time, and whisk constantly. Room temperature cheese melts more smoothly.
- → Can I freeze leftovers?
- Yes, but the texture may change slightly. Freeze for up to 3 months and reheat in the oven with a splash of milk to restore creaminess.